Difenacoum
    Rodenticide Concentrates

    Difenacoum

    Professional
    Difenacoum
    Ratto Ratto grigio Topo domestico

    CAS number


    56073-07-5

    EC number:


    259-978-4

    IUPAC name:

    3-(3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin 

    CAS name:

    3-[3-(1,1’-biphenyl)-4-yl-1,2,3,4-
    tetrahydro-1-naphthalenyl]-
    4-hydroxy-2H-1-benzopyran2-one

    BENEFITS

    • Anticoagulants, such as DIFENACOUM, impair the production
      of vitamin K-dependent coagulation factors by blocking the
      enzyme vitamin K 2,3-epoxide reductase, which regenerates
      vitamin K. This results in the production of dysfunctional
      coagulation factors (Prothrombin, VII, IX, X), leading to
      increased vascular permeability, internal hemorrhage, and
      eventually death.
    • DIFENACOUM’s structural similarity to vitamin K is key to its
      mechanism. Vitamin K serves as an effective antidote, but
      medical advice is essential.

    PROPERTIES

    The rodenticidal properties of DIFENACOUM were described in 1976. DIFENACOUM was also introduced to overcome the early strains of resistant rodents found in the UK and on continental Europe. It is unusual among anticoagulants because, at the LD50 level, it is more potent to house mice than Norway rats but it is also used against rats, including warfarin resistant strains. DIFENACOUM is one of the newer and more potent second-generation anticoagulant rodenticides. DIFENACOUM differs from the first-generation anticoagulants because it is very potent and only requires a single dose to induce death, if sufficient toxicant is ingested. The target organism doesn’t need multiple ingestions to die, once is usually sufficient, thus reducing the quantity of active ingredient useful to control rat or mice population and also reducing the risk of resistance development.

    Storage condition

     

    Store the container tightly closed in a cool, dry place away from food, pets, sunlight, and ignition sources. Keep in hazardous material areas and mix well before use.

    Solubility

    Optimal solubility and stability in glycolic solvents.

    Composition

     

    - BROMADIOLONE is a 4-hydroxycoumarin anticoagulant.
    - Optimal solubility and stability in glycolic solvents.

    PACKAGING

     
    Concentrates offered with
    glycolic solutions    		 Assay Packing Storage
     stability *
    DIFENACOUM 3
    concentration of 30 g/Kg
    of DIFENACOUM    		 standard 25 g/Kg
    (min. 23.8 g/kg)

    25 Kg Plastic Jars
    200 Kg on request

    retest advised
    after 3 years 
    DIFENACOUM 2.5
    concentration of 25 g/Kg
    of DIFENACOUM    		 standard 25 g/Kg
    (min. 23.8 g/kg)

    25 Kg Plastic Jars
    200 Kg on request

    retest advised
    after 1 year  
    DIFENACOUM 0.25
    concentration of 2.5 g/Kg
    of DIFENACOUM    		 standard 2.5 g/Kg
    (min. 2.38 g/kg)

    25 Kg Plastic Jars
    200 Kg on request

    retest advised
    after 3 years