In a market where regulatory expectations are evolving and performance requirements remain uncompromising, formulators are reassessing not only the role of Piperonyl Butoxide (PBO), but also the quality, origin and long-term reliability of the PBO they choose. At Endura, we believe this moment calls for clarity, substance and reassurance: decisions around synergists should be guided not only by immediate efficacy, but by consistency, purity, supply security, sustainability and regulatory resilience over the full product lifecycle.
For more than two decades, Endura has invested in a fully synthetic production route for PBO, supported by industrial-scale manufacturing, controlled and scientifically repeatable chemistry and a clear long-term vision. This was our strategic commitment that continues to benefit our customers today.
Why synthetic PBO remains the more dependable long-term option
1. Consistency and performance you can depend on
Synthetic PBO delivers a reproducible and stable chemical profile from batch to batch. This enables predictable formulation behavior, stable solvency properties, and reliable efficacy across applications, storage conditions and climates.
For formulators, this translates into reduced technical risk and greater confidence that product performance will remain consistent over time.
2. Sustainability with substance, not slogans
For Endura, sustainability is not an add-on, it is a long-term vocation embedded in how we operate and innovate. We have taken a structured step forward with the introduction of voluntary annual sustainability reporting, reinforcing our commitment to transparency and continuous improvement. This reflects our mindset: sustainability must be measurable, accountable and continuously improved.
This approach is supported by tangible industrial actions. At our Ravenna site, we have invested in photovoltaic energy systems (approx. 366 m² surface area, 80.85 kWp installed capacity), contributing to the use of renewable electricity in our operations and reducing our environmental footprint.
More fundamentally, synthetic PBO itself represents the sustainable choice. By eliminating dependence on natural raw materials, it avoids the environmental pressure and variability associated with traditional sourcing. It ensures that supply, quality and environmental impact are controlled, scalable and future-resilient.
Endura was the first company to industrialize this approach, setting the benchmark for high-quality synthetic PBO at scale.
With regard to “bio-based” positioning in the market, it is important to consider that such claims are often difficult to effectively translate into end-use advantages within biocidal formulations. Regulatory frameworks limit the practical applicability of these claims, meaning that their value must be carefully evaluated in a real-world context.
3. Made in Italy: control, quality and long-term reliability
Endura’s PBO is fully manufactured in Italy, within a controlled industrial ecosystem that combines chemical expertise, regulatory discipline and long-standing manufacturing know-how. For customers, this translates into:
controlled and consistent quality standards
a stable and reliable production environment
reduced exposure to uncertainties linked to extra-EU sourcing
This also supports greater predictability in supply and planning, helping customers avoid risks associated with geopolitical or raw-material volatility.
4. Supply security and industrial robustness
Synthetic production enables continuous, large-scale manufacturing based on controlled industrial inputs rather than variable natural feedstocks. This results in:
stronger supply continuity
reduced exposure to disruptions
improved long-term planning reliability
For formulators, supply security is not only an operational benefit, it is a critical factor in maintaining consistent product quality and protecting market positions over time.
5. Regulatory readiness and impurity control: PBO Prime
Over the years, Endura has continuously invested in studies aimed at deepening the understanding of PBO, including its impact on human health and the environment, developing a level of expertise in the properties of the active substance that is both comprehensive and unparalleled in the industry.
In addition, it is important to highlight that Endura has been directly involved in supporting the global regulatory registration of PBO for decades. We actively participate in international task forces and industry working groups, contributing to the scientific and regulatory understanding of this substance at a global level.
Furthermore, regulatory expectations are evolving, with increasing focus on impurity profiles and long-term substance classification. Endura has already proactively addressed this with PBO Prime, our highest-purity PBO grade, developed through a fully synthetic process and advanced patent-pending distillation technology. PBO Prime significantly reduces critical impurities and provides an exceptionally controlled chemical profile.
Endura has concluded that the impurity reduction in PBO Prime does not alter the active substance composition in a way that would require technical equivalence assessment.
In the current EU regulatory context, other PBO sources may still require technical equivalence evaluation, introducing an additional layer of uncertainty for formulators. In practical terms, PBO Prime offers:
enhanced control over impurities
reduced regulatory exposure
improved confidence in long-term compliance
It is the result of years of continuous development aimed at elevating PBO to a higher industrial and regulatory standard.
6. A philosophy of creating wellbeing
At Endura, sustainability is not just an objective, it is part of our identity. We are not simply distributors of wellbeing, but creators of wellbeing through innovation, quality and responsibility.
Our mission is to safeguard human wellbeing through effective pest control solutions while continuously improving the environmental profile of what we produce. This philosophy is fully reflected in our synthetic PBO and in PBO Prime, where years of development have led to further impurity reduction and enhanced product consistency.
Our commitment to you
We know that choosing a synergist is a long-term decision. It is about more than performance: it is about reliability, predictability and future readiness. Our objective is not simply to supply PBO, but to provide a solution that combines:
proven and consistent performance
robust industrial production
high purity and controlled impurity profiles
secure and reliable supply
a credible and structured sustainability approach
excellent technical and regulatory support throughout the product life cycle.
We remain committed to working alongside you as a trusted partner, supporting your formulations today while helping protect your product portfolio for the future. Endura’s approach to PBO is built on consistency, transparency and long-term responsibility.
By combining synthetic production, Made in Italy quality standards, secure supply, proactive regulatory readiness and measurable sustainability actions, we aim to provide solutions you can rely on, today and in the future.