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PBO Prime is a high-grade synergist, the first and only Piperonyl Butoxide (PBO) with the lowest levels of DPE & DPM impurities in the world, well below the thresholds for PBT and vPvB classification under CLP.
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Why choose PBO Prime
- Highest purity grade of PBO
- Fully compliant with the BPR approval of PBO
- Not classifiable as PBT/vPvB
- Lowest levels of DPM and DPE, well below the classification under CLP
This innovation builds on Endura’s legacy: in 1999, we pioneered the first patented synthetic production of PBO, eliminating the need for Sassafras tree harvesting and setting a benchmark for environmental responsibility
Regulatory Challenges
CLP Regulation (EC) No 1272/2008 introduces stricter hazard classifications for PBT and vPvB substances. All substances on the EU market must be reassessed and labeled for these properties by May 2025 and impurities exceeding thresholds can trigger classification under PBT and vPvB criteria.
PBO itself is NOT a PBT neither a vPvB substance.
Two potential impurities in PBO: Dipiperonyl methane (DPM) and Dipiperonyl ether (DPE), could possibly be fulfilling PBT and vPvB criteria. If confirmed to be PBT and vPvB, these two impurities when present in PBO at levels above the CLP threshold could result in the classification of PBO and/or of biocidal products containing PBO, as PBT or vPvB.
PBO Prime in Action
As a powerful synergist, PBO Prime enhances insecticide efficacy while reducing the overall amount of active ingredient needed in formulations.
PBO Prime:
- Reduces the amount of active ingredient required.
- Extends residual activity for longer-lasting protection.
- Helps break insect resistance mechanisms.
Endura Actives
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Activa Formulations
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Our history
- Economic Efficiency: Reduces the amount of active ingredient needed, lowering production costs.
- Enhanced Potency: Increases insecticide effectiveness and helps to break resistance.
- Market Differentiation: Position your product as superior in a crowded market.
- Proactive Implementation: PBO Prime helps you stay ahead of future regulatory development.

"PBO PRIME sets a new standard: the purest PBO on the market, fully compliant and designed to boost your pest control formulations with less regulatory hassle, giving you what matters most: peace of mind, stronger efficacy, and sustainability"

Luca Tabanelli
R&D Director, Endura
With Endura, you choose Innovation, Sustainability and Reliability, ready for the regulatory and performance challenges of tomorrow.